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ARUK Drug Discovery Alliance Meeting

10/10/2025

 
On Thursday 25th September, the Brain Health ARC hosted a meeting at the University of Strathclyde's Neurotechnology Centre for the Alzheimer’s Research UK Drug Discovery Alliance. This was part of the ARUK-DDA “Scottish tour” which had previously encompassed both Edinburgh and Dundee.
Following presentations from the ARUK-DDA: Dr John Skidmore (Cambridge), Prof Fiona Ducotterd (UCL) and Dr Emma Mead (Oxford), there were presentations and in depth discussions about drug discovery from researchers from the University of Strathclyde, the University of Glasgow, and the University of St Andrews. Talks ranged from new potential compounds through to new targets, alongside scientific breakthroughs and new technologies for screening.

​Thanks to Prof Shuzo Sakata from the Strathclyde Neurotechnology Centre for hosting the event and to Prof Frank Gunn-Moore (St Andrews and the Brain Health ARC) for putting together the delegate list. As one of the attendees said: “
It is sometimes just great to hear great science”. 
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The meeting ended with a range of follow up meetings to discuss the individual projects.

Writing Retreat with the Brain Health ARC

9/17/2025

 
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​Written by Amelia McGinley-Brown 

As a recent graduate in Psychology with a specialism in Clinical Health from the University of Glasgow, I knew I didn’t want to lose momentum after finishing my degree. Research has always been a passion of mine, so I was eager to continue to build on the skills I had developed throughout my studies. Before graduating, I was fortunate to meet Professor Terry Quinn, who offered me an incredible opportunity to join the Brain Health ARC as a Voluntary Research Intern.
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A key theme across the four Alliances – and indeed across many sectors – is the importance of interdisciplinary research. My role focuses on exploring researchers’ attitudes toward interdisciplinary collaborations, which gave me the chance to connect with inspiring academics across the UK. This project not only deepened my understanding of the value of interdisciplinary work, but also allowed me to expand and strengthen my quantitative research skills.

​The Brain Health ARC is currently leading efforts to highlight Scotland as a global hub for brain health research and innovation. One way they
have done so recently is hosting a writing retreat at the Scottish Centre for Ecology and the National Environment (SCENE), in Loch Lomond – a highlight of my internship (so far). Here I was able to meet and learn from incredible people who are driving forward innovative research. 
I feel truly grateful for these experiences, which have strengthened my skills, broadened my perspective, and further fuelled my passion for research in brain health and beyond. ​
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The writing retreat at SCENE allowed for time away in a distraction-free zone, which felt like a gift. Being in such a beautiful, calming place surrounded by greenery and water was exactly what I needed to reset and refocus. Not only did I get so much done, but I also had the chance to just breathe, reflect, and soak in the atmosphere.  ​
The first day welcomed us with lovely weather (which obviously did not last long), which made for a refreshing walk along the beach shortly after arriving. It was the perfect icebreaker to get to know everyone and hear about their goals for the retreat.

​The
evening that followed was filled with a tasty dinner, plenty of laughter, and a fun quiz (which my team won! – definitely not bragging). 
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Day two was more work-focused but just as rewarding. The talks on careers paths, tips and tricks for securing a grant/fellowship and the networking opportunities throughout the retreat were truly invaluable. During Lisa Kidds' talk, she shared how she navigated the uncertainty of early career research, and it was such a reassuring moment – I realised I am not alone in feeling unsure about the future and that there is no single ‘right’ path. It was a reminder that pauses, reflection, and connecting with others are just as important as the work itself. 
Throughout the day (and some late-night work with my new friends) I managed to finish writing my introduction and even squeezed in a few interviews, which felt like a real accomplishment. There is something incredibly motivating about being surrounded by others who are deeply focused on their work – the energy is contagious, and I found myself settling into my writing faster than I ever do at home. 

On the final day, I wrapped up more interviews and faced the bittersweet moment of having to leave. It was hard to say goodbye to such a supportive environment, especially after just starting to feel so connected and motivated.   ​
One of the most valuable parts of the retreat was hearing everyone’s journey of how they got to where they are today. As someone in that strange in-between stage of not quite knowing what the future holds, it was incredibly reassuring to hear to such open and honest stories. It reminded me that even the most established researchers once stood where I am now, figuring things out step-by-step.

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Looking back, the retreat was more than just productive – it was grounding, inspiring, and exactly what I needed at this point in my journey. I left feeling reassured that uncertainty is part of the process. I also felt motivated by the people I met and grateful for the reminder that sometimes stepping away from the noise is the best way to move forward.

​The retreat reminded me of the power of connecting with others, learning from their experiences, and creating the space to focus on my own work.
It was an invaluable experience that I'm extremely grateful for. 
 
 
Photograph credit to Kalliopi Mavromati & Angelina Kirilova Kancheva.

AAIC 2025 with Angelina and Kalli

8/21/2025

 
Two prize winning early career researchers, Angelina Kancheva and Kalliopi Mavromati, share their experiences of attending the world's biggest dementia conference, the Alzheimer's Association International Conference (AAIC).
Hi all! I am Angelina, a final-year Medical Research Council-funded PhD student on the Precision Medicine Doctoral Training Program, based at the University of Glasgow. My research aims to describe clinical phenotypes related to small vessel disease in the brain using large population-based studies, such as UK Biobank. As part of my PhD, I have also conducted some research on the link between cardiovascular risk and blood-based Alzheimer's disease biomarkers in cognitive impairment. In my free time, I am a keen trail runner and adventure traveller! I love exploring new places, cultures, and ways of being. 
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Last year, I was one of the researchers who took part in the Brain Health ARC Bio-Hermes Biomarker Data Challenge. I was very eager to explore this deeply characterised, exciting dataset and try to answer a clinically relevant research question that I am passionate about. I  led a project looking at cardiovascular risk as a moderator of the relationship between blood-based Alzheimer's disease biomarkers and cognitive status. I was honoured to be among the winners of the Data Challenge awarded by Global Alzheimer's Platform Foundation and, after a successful abstract application, I presented my project "Investigating Cardiovascular Risk as a Moderator of the Relationship between Blood-Based Alzheimer’s Disease Biomarkers and Cognitive Impairment – A Cross-sectional Analysis of Data from the Bio-Hermes Study" at AAIC 2025 in Toronto! I have to acknowledge the generous support of Guarantors of Brain and the College of Medical, Veterinary & Life Sciences who funded my conference attendance. 
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For me, the absolute highlight of AAIC was the scale of the conference. I don't think I have ever attended such a big scientific meeting (and I've been privileged to present my research at various local and international conferences) - there was a special, palpable energy to it and, quite frankly, it was impossible not to feel inspired after a few days of great science and excellent talks on the state-of-the-art in dementia research. I was very keen to make the most of the conference and registered to attend the two pre-conference days as well, which featured a fantastic full day on fluid biomarkers and Alzheimer’s Imaging Consortium day. 

I was also happy that my work was received very well and that I was able to make new connections, which could potentially lead to fruitful future collaborations. The networking at AAIC was crazy - it genuinely felt like a regular conference on steroids - everyone was there, willing to chat and discuss science, research, jobs, and what to do in Toronto. I also really enjoyed the additional fun activities on offer, particularly the energizing AAIC 5K at sunrise along lake Ontario!

Now that I am approaching the final stages of my PhD, I have come to appreciate that I have been able to meet some great people through research from different backgrounds and walks of life. I can even call some of them friends! And connections matter so much in science and research!
For me, the biggest challenge was putting myself out there and confidently approaching people to discuss potential postdoc opportunities or simply ask for a chat. The end of a PhD is a strange time; you have been in higher education for so long, particularly if you have done an undergraduate degree and a master's; you have so many years of experience behind you, yet, it feels like the real journey is only just beginning. Through my education, I have been fortunate to study in several different countries, which has allowed me to experience diverse research environments and cultures.

Going forward, I would like to establish myself as an independent researcher and I am currently working towards that goal and reflecting on the best next step. It is an exciting time, but also one that presents itself with additional challenges and difficulties. You have to think quite carefully about who you would want to be in the field where you want to learn, develop and grow, and choose who you work with as well. 
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My main takeaway from AAIC 2025 is that the world is yours if you want it to be. One has to work very hard, with integrity, passion, and commitment, but hard work pays off. While I am scientifically minded, I also believe in serendipity, and I think that's a good word to summarise my conference! 
Hopefully, by next year's AAIC in London I will have several exciting professional updates to share, but for now, I am focusing on finishing up my PhD and preparing for the next big step! 

Hi, I'm Kalli! I'm a researcher at the University of Glasgow. I have a background in psychology with specialism in neuroscience, plus diverse experience as a statistician.

​In recent years, I have been developing and testing a virtual assistant for stroke survivors with Registry for Stroke Care Plus (RESQ+) and I managed the BioHermes001 Data Challenge.

​During the challenge, I also led projects that operationally define the risk and resilience to Alzheimer's disease and received the best overall talk award at the challenge showcase! For this, I was very generously sponsored to travel to the Alzheimer's Association International Conference 2025. ​
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The Global Alzheimer's Platform Foundation (GAP) and Alzheimer's Disease Data Initiative (ADDI) provided me with an opportunity I would have otherwise been completely unable to access, as I'm a research assistant but not a PhD student or an independent researcher (yet!). This means I am ineligible for most schemes that would enable my attendance at an international destination like Toronto. Thanks to this very generous gift, I was able to travel to Toronto with my colleague Stelios and attend all four days of the conference. It was also my first time crossing the Atlantic and the longest flight I have ever been on (7:30 hours from Glasgow to Toronto!)
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​At AAIC, I had the opportunity to share what we achieved with the Data Challenge at a featured research session on data sharing. The session focused on infrastructure issues and data governance considerations, and GAP Foundation President, John Dwyer, and I shared the importance of empowering researchers and bringing together the research community to accelerate dementia research. It was an honour to share the podium with him and to be on a panel with leaders in the field, including Professor Sarah Bauermeister of Dementias Platform UK at the University of Oxford, who has inspired a lot of my professional development in the lead-up to the talk. Outside of research, I also had the opportunity to finally meet the GAP Foundation team with whom I worked throughout the challenge! The team have truly made me feel celebrated for my award and it was so exciting to connect in person.
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​Connecting with researchers from whom I have learned and want to learn so much from was the biggest highlight. From stimulating conversations about the pathogenic mechanisms over drinks at receptions, to envisioning equity in brain health research with Atlantic Fellows over delicious food, I felt inspired, invigorated, and "propelled forward" as someone important to me has once described my takeaways from events like this.

A highlight for me was getting to speak to the female scientists I look up to as an aspiring research leader. I'm thinking of the incredible Dr Lynne Hughes, the pioneering Dr Maura Malpetti, the wonderfully creative Dr Liz Yuanxi Lee, and my amazing friend (soon to be Dr) Angelina Kancheva. So many brilliant researchers dedicated time to discussing my research vision as I prepare for next steps to transition to research independence, and their perspectives, feedback, and questions have transformed my outlook on my own value as a researcher and the potential of my envisioned work programme to create change.
Okay okay and Toronto was also just amazing. My room had a beautiful view out to the lake (which I then saw as I flew out to Boston at the end of the conference!) and I enjoyed getting a sunrise run in and feeling the city vibes after work, though I have to say I was a little scared when I got to the top of the CN tower! You can follow my instagram for vlogs that better capture the "vibes" and my bluesky for the most exciting scientific things I heard during the conference.

The experience was difficult for me as a neurodivergent adult and I find it impossible to discuss my attendance outside the context of how difficult it was to meet my support needs at a conference with a constantly running schedule between 0630 and 2300. It was clear that the organisers had made creating spaces for this purpose a priority, and that is appreciated, however the schedule demands were gruelling and the crowds were impossible to avoid. I feel vulnerable sharing this, but I required about 10 days isolation and exclusive working from home to regulate and return to my "normal". I am certain I am not alone in this, and I wish that needing time to recover after such experiences was normalised and supported by the teams to which professionals return after such experiences.

Yes, I would travel a day before so I have more time to adjust, and I would prioritise things like my morning runs, even if it means ending evening activities a little early for some sleep. I would also get a sunflower pin (like my sunflower lanyard but in pin form) so I could have a discrete signal on my conference lanyard of my hidden disability so that it is clear I may need more time or space in some instances. 

​I left the conference empowered to continue pursuing my research vision. I felt inspired by the scientific developments I got to hear about and I have no doubt that creative interdisciplinary leadership holds the key to future growth in my field of mapping pathogenesis before amnesic symptom onset. I felt proud to cheer on my friends, and seen by those who support me, a cherry on top of a uniquely transformative experience.

INT-ACT Project Update

8/20/2025

 
We’re pleased to spotlight a new initiative supported by Brain Health ARC seed funding with Sofía de la Fuente García and INT-ACT!

​The project, “Evaluating the Impact of Intangible Cultural Heritage Experiences on the Wellbeing of Older Adults with Cognitive Impairment: A Pilot Study in Scotland”, will explore how immersive heritage can support wellbeing, reduce social isolation, and expand access to cultural participation in older adults. 

​This initiative reflects INT-ACT’s broader mission to address societal challenges through cultural heritage, with a specific case study on ageing societies, which the University of Edinburgh is leading on. By extending participation to a population that is vulnerable to social isolation and less exposed to technology, the team is promoting more inclusive approaches in heritage, technological, and health domains.
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 Sofía de la Fuente García
Having recently received ethics approval, recruitment will soon begin through Join Dementia Research. Data collection will then commence in Edinburgh later this year, alongside an idle exhibition for visitors to find out more.

Discover more about the project here.
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The Brain Health Alliance for Research Challenges is supported by the Scottish Funding Council.
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